Helicobacter pylori Hp A-26

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Hp A-26 is a Gram-negative bacterium characterized by its spirilla shape and microaerophilic oxygen requirement. This organism is typically found in a host-associated habitat, predominantly within the gastric mucosa of humans. Notably, it exists as single cells rather than in clusters or chains. H. pylori Hp A-26 possesses a single replicon and is surrounded by two membranes, a trait common to Gram-negative bacteria. The bacterium is non-motile despite the presence of flagella, which suggests that its movement may be limited or reliant on other mechanisms within its environment. It thrives optimally at 37°C, indicating a mesophilic temperature range suitable for growth in warm-blooded hosts. This bacterium exhibits a free-living biotic relationship, suggesting that it can survive independently in its environment, although its primary habitat is within a host. The accession number for this strain is AKOV00000000.1, providing a reference for further genetic and genomic studies. The ecological insight regarding H. pylori Hp A-26 highlights its adaptation to a specific niche within the gastric environment, where it can influence gastrointestinal health and disease. Its microaerophilic nature and preference for a mesophilic temperature suggest specialized metabolic pathways that allow it to thrive in conditions that are less favorable for other organisms. Understanding these traits can enhance the knowledge of H. pylori's role in human health and disease progression.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp A-26

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp A-26
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp A-26 HpA_26.contig.8_1, whole genome

Gene Summary

Adenine Count

496658 bp

Thymine Count

494648 bp

Guanine Count

319649 bp

Cytosine Count

313238 bp

Genome Length

1624194 bp

Protein-coding Genes

1668 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
n-succinyldiaminopimelate aminotransferaseHPHPA26_0628Not AvailableNegative619192 - 62031943163.6
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthaseHPHPA26_0629Not AvailablePositive620473 - 62155239259.2
2,3,4,5-tetrahydropyridine-2-carboxylate n-succinyltransferaseHPHPA26_0630Not AvailablePositive621555 - 62276044151.1
cysteine-rich protein fHPHPA26_0631Not AvailablePositive622772 - 62383038144.9
hypothetical proteinHPHPA26_0632Not AvailablePositive623976 - 62602179772.9
nad(p)h quinone dehydrogenase mdabHPHPA26_0633Not AvailableNegative626076 - 62666021581.8
quinone-reactive ni/fe hydrogenase, small subunitHPHPA26_0634Not AvailablePositive626821 - 62797542331.5
quinone-reactive ni/fe-hydrogenaseHPHPA26_0635Not AvailablePositive627985 - 62972164447.4
ni/fe-hydrogenase, b-type cytochrome subunitHPHPA26_0636Not AvailablePositive629734 - 63040825807.8
hydrogenase expression/formation proteinHPHPA26_0637Not AvailablePositive630405 - 63094119607.0

Displaying genes 631 – 640 of 1709 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.