Helicobacter pylori Hp H-16

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori Hp H-16 is a Gram-negative bacterium characterized by its spiral shape (spirilla) and single-cell arrangement. This microbe thrives optimally at a temperature of 37.0°C, which aligns with its adaptation to the human gastric environment, where it is primarily found. H. pylori Hp H-16 is classified as microaerophilic, indicating that it requires a reduced level of oxygen for growth, a feature that allows it to inhabit the acidic conditions of the stomach while avoiding complete exposure to atmospheric oxygen. As a host-associated organism, H. pylori Hp H-16 plays a significant role in the microbiota of the gastric niche, where it can influence local pH levels and interact with the host's immune response. The unique combination of its morphology, growth conditions, and habitat suggests that H. pylori Hp H-16 has evolved specialized adaptations for survival and proliferation in the challenging gastric environment, highlighting the intricate relationships between microbial life and host physiology. Understanding these traits can provide insights into the broader implications of H. pylori in human health and disease, particularly in relation to its ecological role within the gastrointestinal tract.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainHp H-16

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori Hp H-16
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori Hp H-16


Gene Summary

Adenine Count

513752 bp

Thymine Count

528531 bp

Guanine Count

333965 bp

Cytosine Count

333386 bp

Genome Length

1709635 bp

Protein-coding Genes

1686 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
type i restriction modification dna specificity domain family proteinHPHPH16_0001Not Available+20 - 2538921.82
outer membrane protein hoffHPHPH16_0002Not Available-468 - 196756966.2
liporelease system transmembrane proteinHPHPH16_0003Not Available-2246 - 347846043.2
preprotein translocase, seca subunitHPHPH16_0004Q9ZL57-3468 - 606599011.1
outer-membrane lipocarrier proteinHPHPH16_0005Q9ZL58+6212 - 676621422.2
Tmrna,resume consensus sequence (at 77): aataactgtaaacaacgcNot AvailableNot Available+6822 - 7207Not Available
hypothetical proteinHPHPH16_0006Not Available+7251 - 777819998.9
outermembrane protein hofeHPHPH16_0007Not Available-7785 - 915252058.8
hypothetical proteinHPHPH16_0008Not Available-9250 - 1053949506.1
hypothetical proteinHPHPH16_0009Not Available+10533 - 107096880.6

Displaying genes 1 – 10 of 1728 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

92 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 92 metabolites