Helicobacter felis ATCC 49179

Gram-negativeSpirillaMotileAerobic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter felis is a microaerophilic, urease-positive, spiral-shaped bacterium found in the stomach of cats and dogs. They grow as rigid, spiral-shaped, gram-negative cells that are 0.4 um wide, 5 to 7.5 um long and have five to seven spirals per cell. This strain (the type strain) was isolated from the gastric mucosa of a cat. H. felis infection in cats induces lymphoid follicular hyperplasia, mild gastritis, and seroconversion, but is associated with normal gastric secretory function. It has also been isolated from humans with acute gastritis (adapted from PMID 1704791 and 10639446). (EBI Integr8)

Taxonomy

Kingdom	Pseudomonadati
Phylum	Campylobacterota
Class	Epsilonproteobacteria
Order	Campylobacterales
Family	Helicobacteraceae
Genus	Helicobacter
Species	Helicobacter felis
Strain	ATCC 49179

Profile

Physiology
Gram staining properties	Negative
Shape	Spirilla
Mobility	Yes
Flagellar presence	Yes
Number of membranes	2

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Aerobic
Optimal temperature	Not Available
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Not Available
Cell arrangement	Singles
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Helicobacter felis ATCC 49179

NC_014810.2

Gene Summary

Adenine Count

463222 bp

Thymine Count

464971 bp

Guanine Count

375764 bp

Cytosine Count

368723 bp

Genome Length

1672681 bp

Protein-coding Genes

1642 genes

Non-Coding Genes

69 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
acetate kinase	HFELIS_RS04855	Not Available	Negative	958422 - 959621	44168.3
phosphate acetyltransferase	HFELIS_RS04860	Not Available	Negative	959625 - 961112	53070.2
shikimate kinase	HFELIS_RS04865	Not Available	Negative	961151 - 961642	18170.0
phosphopyruvate hydratase	HFELIS_RS04870	Not Available	Negative	961626 - 962894	45773.7
outer membrane beta-barrel protein	HFELIS_RS04875	Not Available	Negative	962947 - 963588	23721.9
mlae family lipid abc transporter permease subunit	HFELIS_RS04880	Not Available	Positive	963693 - 964802	41124.6
abc transporter atp-binding protein	HFELIS_RS04885	Not Available	Positive	964811 - 965593	29474.0
mlad family protein	HFELIS_RS04890	Not Available	Positive	965578 - 966411	30817.7
hypothetical protein	HFELIS_RS04895	Not Available	Positive	966408 - 966995	21185.2
sel1-like repeat protein	HFELIS_RS04900	Not Available	Positive	967005 - 968687	61520.8

Displaying genes 1001 – 1010 of 1711 in total

Pathways

1216 pathways

2,3-Dihydroxybenzoate Biosynthesis

Lysine Biosynthesis

Taurine Metabolism

Palmitate Biosynthesis

Fatty Acid Elongation (Saturated)

tRNA Charging

Glycine Biosynthesis

Threonine Biosynthesis

Show All 1216 Pathways

Metabolite ID	Metabolite name	CAS number	Average mass Monoisotopic mass
BASm0000260	3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5	Not available	Average405.556Da Monoisotopic405.264647871Da
BASm0000428	3-oxoadipateC6H6O5	Not available	Average158.11Da Monoisotopic158.022620453Da
BASm0000592	(S)-1-phenylethanolC8H10O	Not available	Average122.1644Da Monoisotopic122.0731649Da
BASm0000989	GlycerolC3H8O3	`56-81-5`	Average92.0938Da Monoisotopic92.04734412Da
BASm0001225	dodecanoateC12H23O2	Not available	Average199.3098Da Monoisotopic199.169805Da
BASm0001661	Cu(2+)Cu	`7440-50-8`	Average63.546Da Monoisotopic62.929601079Da
BASm0001865	diphosphateHO7P2	Not available	Average174.95Da Monoisotopic174.9213971Da
BASm0002157	7-cyano-7-deazaguanineC7H5N5O	Not available	Average175.1475Da Monoisotopic175.0494098Da
BASm0002319	Cu(+)Cu	`7440-50-8`	Average63.546Da Monoisotopic62.92960108Da
BASm0002626	(6Z,9Z,12Z)-octadecatrienoyl-CoAC39H60N7O17P3S	Not available	Average1023.92Da Monoisotopic1023.300119988Da