Lactobacillus crispatus ST1

Gram-positiveRodNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Lactobacillaceae

Genus

Lactobacillus

Description

Lactobacilli are normal inhabitants of the gastrointestinal tract of man and animals where they are widely considered to exert a number of beneficial roles including immunomodulation, interference with enteric pathogens, and maintenance of a healthy intestinal microflora. Historically, probiotic roles have been ascribed primarily to Lactobacillus acidophilus. The genus Lactobacillus presently comprises more than 50 recognized species of non-pathogenic bacteria which in addition to their probiotic effects are useful to human as indispensable agents for the fermentation of foods and feed. Lactobacillus crispatus (strain ST1) is a Gram-positive bacterium isolated from the crop of a chicken. L. crispatus displays a strong protein-dependent adhesion to the epithelial cells of the human vagina and has been shown to inhibit the adhesion of avian pathogenic Escherichia coli. It is also a member of the normal oral and gastrointestinal tract microflora. (Adapted from PMID: 20435723). (EBI Integr8)

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyLactobacillaceae
GenusLactobacillus
SpeciesLactobacillus crispatus
StrainST1

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Lactobacillus crispatus ST1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementChains
SporulationNot Available
Energy sourceNot Available
PathogenicityNo

Genome Summary

Lactobacillus crispatus ST1, complete sequence.

Gene Summary

Adenine Count

648455 bp

Thymine Count

640646 bp

Guanine Count

381836 bp

Cytosine Count

371633 bp

Genome Length

2043161 bp

Protein-coding Genes

1960 genes

Non-Coding Genes

85 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glycosyltransferase family 8 proteinLCRIS_RS00355Not AvailableNegative72003 - 7283932704.4
lysophospholipid acyltransferase family proteinLCRIS_RS00360Not AvailableNegative72856 - 7361729555.8
Trna-lysNot AvailableNot AvailablePositive73797 - 73869Not Available
hypothetical proteinLCRIS_RS00370Not AvailableNegative74002 - 742238241.62
Trna-lysNot AvailableNot AvailablePositive74342 - 74414Not Available
response regulator yycfLCRIS_RS00380Not AvailablePositive74551 - 7526727495.2
cell wall metabolism sensor histidine kinase walkLCRIS_RS00385Not AvailablePositive75338 - 7719169261.6
yych family regulatory proteinLCRIS_RS00390Not AvailablePositive77172 - 7853352757.2
two-component system regulatory protein yyciLCRIS_RS00395Not AvailablePositive78536 - 7936031464.1
mbl fold metallo-hydrolaseLCRIS_RS00400Not AvailablePositive79373 - 8017029199.3

Displaying genes 81 – 90 of 2045 in total

Metabolites

127 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm00011795-hydroxyisourateC5H4N4O4Chemical structure of 5-hydroxyisourateNot available
Average184.1097Da
Monoisotopic184.0232546Da
BASm0001639CobinamideC48H72CoN11O8Chemical structure of Cobinamide13497-85-3
Average990.0874Da
Monoisotopic989.4897335Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm00022412-demethylmenaquinone-8C50H70O2Chemical structure of 2-demethylmenaquinone-8Not available
Average703.0896Da
Monoisotopic702.5375815Da
BASm00026123-oxohexadecanoyl-CoAC37H64N7O18P3SChemical structure of 3-oxohexadecanoyl-CoANot available
Average1019.926Da
Monoisotopic1019.324139Da
BASm0002780orotidine 5'-phosphateC10H10N2O11PNot available2149-82-8
Average365.168Da
Monoisotopic365.003866888Da

Displaying 1–10 of 127 metabolites

Health Effects

No health effects information available for this bacterium.