Helicobacter pylori 52

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori 52 is a Gram-negative bacterium characterized by its spirilla shape and solitary cell arrangement. This microbe thrives in microaerophilic conditions, indicating a requirement for reduced oxygen levels for optimal growth. H. pylori 52 is typically found in host-associated habitats, suggesting a close association with its host organisms. The optimal growth temperature for this strain is approximately 37.0°C, which corresponds to the average body temperature of mammals, further emphasizing its adaptation to a host environment. Helicobacter pylori is well-known for its role in gastrointestinal microbiota, particularly in the human stomach, where it can survive the acidic conditions. This adaptability is facilitated by various physiological and biochemical mechanisms that allow it to colonize the gastric mucosa. Understanding the specific traits of H. pylori 52 can provide insights into its ecological niche and potential interactions within its host. The microaerophilic nature of H. pylori 52 suggests that it may play a role in maintaining the delicate balance of the gastrointestinal microbiome, potentially influencing host health and disease processes. Its ability to thrive at body temperature and within the host environment underscores the complex relationships that exist between microbes and their hosts, highlighting the importance of studying such organisms to better understand microbial ecology and host interactions.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain52

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori 52
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori 52, complete sequence.

Gene Summary

Adenine Count

476943 bp

Thymine Count

480968 bp

Guanine Count

303000 bp

Cytosine Count

307915 bp

Genome Length

1568826 bp

Protein-coding Genes

1461 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Ncrna_class:srp_rnaNot AvailableNot AvailablePositive16775 - 16872Not Available
cog3014 family proteinHPKB_RS00110Not AvailablePositive17046 - 1838651038.7
chemotaxis protein chev1HPKB_RS00115O24864Positive18487 - 1945236535.1
carboxynorspermidine decarboxylaseHPKB_RS00120A8FNH9Positive19449 - 2066645875.1
lipid a 1-phosphatase lpxeHPKB_RS00125O24866Negative20676 - 2120919617.7
phosphoethanolamine--lipid a transferase eptaHPKB_RS00130O24867Negative21259 - 2283059075.4
saba family sialic acid-binding adhesinHPKB_RS00135Not AvailableNegative23272 - 2533574859.4
dna/rna non-specific endonucleaseHPKB_RS00140Not AvailablePositive25581 - 2597315473.4
prephenate dehydrogenaseHPKB_RS00145P20692Negative26221 - 2704830428.4
endopeptidase laHPKB_RS00150P55995Negative27073 - 2956893829.5

Displaying genes 21 – 30 of 1506 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

92 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 92 metabolites

Health Effects

No health effects information available for this bacterium.