Helicobacter pylori 52

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori 52 is a Gram-negative bacterium characterized by its spirilla shape and solitary cell arrangement. This microbe thrives in microaerophilic conditions, indicating a requirement for reduced oxygen levels for optimal growth. H. pylori 52 is typically found in host-associated habitats, suggesting a close association with its host organisms. The optimal growth temperature for this strain is approximately 37.0°C, which corresponds to the average body temperature of mammals, further emphasizing its adaptation to a host environment. Helicobacter pylori is well-known for its role in gastrointestinal microbiota, particularly in the human stomach, where it can survive the acidic conditions. This adaptability is facilitated by various physiological and biochemical mechanisms that allow it to colonize the gastric mucosa. Understanding the specific traits of H. pylori 52 can provide insights into its ecological niche and potential interactions within its host. The microaerophilic nature of H. pylori 52 suggests that it may play a role in maintaining the delicate balance of the gastrointestinal microbiome, potentially influencing host health and disease processes. Its ability to thrive at body temperature and within the host environment underscores the complex relationships that exist between microbes and their hosts, highlighting the importance of studying such organisms to better understand microbial ecology and host interactions.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain52

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori 52
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori 52, complete sequence.

Gene Summary

Adenine Count

476943 bp

Thymine Count

480968 bp

Guanine Count

303000 bp

Cytosine Count

307915 bp

Genome Length

1568826 bp

Protein-coding Genes

1461 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
type i restriction endonuclease subunit rHPKB_RS07265Q60295Positive1494900 - 1497875115669.0
sprt family zinc-dependent metalloproteaseHPKB_RS07270Not AvailablePositive1497875 - 149858228155.5
tonb-dependent receptor family proteinHPKB_RS07275Not AvailableNegative1498671 - 150119694628.2
arginaseHPKB_RS07280Q58DL1Negative1501704 - 150267236906.9
amino acid permeaseHPKB_RS07285O31462Negative1502685 - 150411251978.8
alanine dehydrogenaseHPKB_RS07290Q08352Positive1504312 - 150545440923.1
duf262 domain-containing proteinHPKB_RS07295Not AvailablePositive1505578 - 150729067216.2
outer membrane proteinHPKB_RS07300Not AvailableNegative1507301 - 150802926940.8
nad(+)/nadh kinaseHPKB_RS07305B6JP37Positive1508215 - 150906931567.2
dna repair protein recnHPKB_RS07310O25943Positive1509082 - 151065659455.8

Displaying genes 1431 – 1440 of 1506 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

92 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001697(S)-4,5-dihydroxypentane-2,3-dioneC5H8O4Chemical structure of (S)-4,5-dihydroxypentane-2,3-dioneNot available
Average132.1146Da
Monoisotopic132.042258744Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001779orotateC5H3N2O4Chemical structure of orotateNot available
Average155.09Da
Monoisotopic155.0098302Da

Displaying 1–10 of 92 metabolites

Health Effects

No health effects information available for this bacterium.