Blautia obeum A2-162

Gram-positiveCocciNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Blautia

Description

Blautia obeum A2-162 is a microbe that thrives in a temperature range of 37°C to 42°C, classified as thermophilic. It is a chemoheterotroph that derives its energy from the breakdown of organic compounds, specifically amino acids and sugars. This microbe produces energy through anaerobic respiration, utilizing alternate electron acceptors in the absence of oxygen. Gram-staining reveals that Blautia obeum A2-162 has a Gram-positive cell wall, indicating a thick peptidoglycan layer. The microbe's shape is irregular, with a long, curved, or branched cell morphology. It is found in all body sites, including the gut, skin, and respiratory tract, across all possible species. Oxygen preference is characterized as a facultative anaerobe, meaning that while it can survive in the presence of oxygen, it can also thrive in its absence. Further investigation reveals that Blautia obeum A2-162 is a crucial member of the human gut microbiome, playing a role in the breakdown of dietary polysaccharides and amino acids. It has been isolated from human faeces and shown to dominate in the gut of patients with irritable bowel syndrome (IBS). Notably, Blautia obeum A2-162 has been proposed as a potential probiotic, due to its ability to modulate the gut microbiome and alleviate symptoms of IBS. Its unique metabolic properties make it an attractive target for further research into the treatment of gastrointestinal disorders.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusBlautia
SpeciesBlautia obeum
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Blautia obeum A2-162
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatAnimal intestinal microflora
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Blautia obeum A2-162

Accession NumberNC_021022.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

3506 genes

Non-Coding Genes

68 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
AttlNot AvailableNot Available+783027 - 783038Not Available
site-specific integraseCK5_RS18425Not Available+791066 - 79227344896.6
AttlNot AvailableNot Available+792533 - 792549Not Available
pbecr4 domain-containing proteinCK5_RS03845Not Available+792960 - 79326211396.4
Hybrid sensor histidine kinase - response regulatorCK5_RS03850Not Available-793375 - 79367411131.4
cd1871a family cxxc motif-containing proteinCK5_RS03855Not Available+793731 - 7938955647.31
4fe-4s binding proteinCK5_RS03860Not Available+793888 - 79485635525.2
tlpa family protein disulfide reductaseCK5_RS03865Not Available+794870 - 79583835051.3
Terminase large subunitCK5_RS03870Not Available+795844 - 79661729853.5
hypothetical proteinCK5_RS03875Not Available+796717 - 79704012288.7

Displaying genes 1 – 10 of 3574 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

267 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm00011795-hydroxyisourateC5H4N4O4Chemical structure of 5-hydroxyisourateNot available
Average184.1097Da
Monoisotopic184.0232546Da
BASm0001360methanesulfonateCH3O3SChemical structure of methanesulfonate59721-29-8
Average95.09Da
Monoisotopic94.980838711Da
BASm0001639CobinamideC48H72CoN11O8Chemical structure of Cobinamide13497-85-3
Average990.0874Da
Monoisotopic989.4897335Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da

Displaying 1–10 of 267 metabolites