Arcanobacterium haemolyticum DSM 20595

Gram-positiveRodNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Actinomycetales

Family

Actinomycetaceae

Genus

Arcanobacterium

Description

Arcanobacterium haemolyticum DSM 20595 is a gram-positive, rod-shaped bacterium that prefers mesophilic temperatures (optimal growth at around 30–37°C). Classified as a chemoheterotroph, this organism derives its energy and carbon from organic matter, making it reliant on the consumption of existing biomass. It is also categorized as a facultative anaerobe, capable of functioning in both aerobic and anaerobic environments. This microbe is often found in various body sites, particularly in human skin, throat, and respiratory tract. Its presence is notable as it can be part of the normal microbiota; however, it has been implicated in opportunistic infections, especially in immunocompromised individuals. The ability to thrive in different environments underscores its adaptability and importance in clinical microbiology. Arcanobacterium haemolyticum is noteworthy for its hemolytic activity, which can lead to lysis of red blood cells. This characteristic is especially significant in laboratory identification, as it can be detected through hemolysis on blood agar. The organism has been associated with pharyngitis and skin infections, particularly in adolescents and young adults, leading to confusion with streptococcal infections. The ability of A. haemolyticum to produce specific virulence factors, including toxins, also contributes to its pathogenic potential. Research has indicated that the bacterium may have a role in contributing to inflammatory responses, which could further complicate infections in susceptible populations. Additionally, its increasing recognition as a pathogen highlights the need for heightened awareness in clinical settings to ensure appropriate diagnosis and treatment.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderActinomycetales
FamilyActinomycetaceae
GenusArcanobacterium
SpeciesArcanobacterium haemolyticum
StrainDSM 20595

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Arcanobacterium haemolyticum DSM 20595
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipSymbiotic
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityYes

Genome Summary

Arcanobacterium haemolyticum DSM 20595

Accession NumberNC_014218.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1791 genes

Non-Coding Genes

76 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
AttlNot AvailableNot Available+1668963 - 1668978Not Available
Isrso12-transposase orfb proteinARCH_RS09995Not Available-1673203 - 167366418032.4
Is1477 transposaseARCH_RS07705Not Available-1673820 - 167414912183.7
sdpi family proteinARCH_RS10535Not Available+1674348 - 167463811439.9
hypothetical proteinARCH_RS07715Not Available+1675656 - 167653732273.5
methyltransferaseARCH_RS07720Not Available+1676524 - 167763041029.4
hypothetical proteinARCH_RS07725Not Available-1677780 - 167862529901.5
nlpc/p60 family proteinARCH_RS10540Not Available-1678622 - 16787684807.82
Distal tail proteinARCH_RS07730Not Available-1678915 - 167960724241.2
Tape measure proteinARCH_RS07735Not Available-1679607 - 168188482084.2

Displaying genes 1 – 10 of 1867 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

221 records
Metabolite IDMetabolite nameStructureCAS number
BASm0014037Fumaric acidC4H4O4Chemical structure of Fumaric acid110-17-8
Average116.0722Da
Monoisotopic116.010958616Da
BASm0014038Malic acidC4H6O5Chemical structure of Malic acid97-67-6
Average134.0874Da
Monoisotopic134.021523302Da
BASm0014039L-Lactic acidC3H6O3Chemical structure of L-Lactic acid79-33-4
Average90.0779Da
Monoisotopic90.031694058Da
BASm0014041Oleic acidC18H34O2Chemical structure of Oleic acid112-80-1
Average282.4614Da
Monoisotopic282.255880332Da
BASm0014042Oxoglutaric acidC5H6O5Chemical structure of Oxoglutaric acid328-50-7
Average146.0981Da
Monoisotopic146.021523302Da
BASm0014044Orotic acidC5H4N2O4Chemical structure of Orotic acid65-86-1
Average156.0963Da
Monoisotopic156.017106626Da
BASm0014045Propionic acidC3H6O2Chemical structure of Propionic acid79-09-4
Average74.0785Da
Monoisotopic74.036779436Da
BASm0014058Myristic acidC14H28O2Chemical structure of Myristic acid544-63-8
Average228.3709Da
Monoisotopic228.20893014Da
BASm0014059Stearic acidC18H36O2Chemical structure of Stearic acid57-11-4
Average284.4772Da
Monoisotopic284.271530396Da
BASm0014065N-AcetylmannosamineC8H15NO6Chemical structure of N-Acetylmannosamine7772-94-3
Average221.2078Da
Monoisotopic221.089937217Da

Displaying 41–50 of 221 metabolites