Porphyromonas uenonis 60-3

Gram-negativeRodAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Porphyromonadaceae

Genus

Porphyromonas

Description

Porphyromonas uenonis 60-3 is a gram-negative, rod-shaped bacterium that thrives in anaerobic conditions, making it an obligate anaerobe. This microbe prefers a mesophilic temperature range, typically falling between 25°C and 37°C, which aligns well with its ecological niches. As a chemoheterotroph, Porphyromonas uenonis 60-3 utilizes organic compounds as its source of carbon and energy, often degrading proteins and other complex molecules in its environment. This organism is primarily found in the oral cavity, specifically within dental plaque and periodontal pockets, where it plays a role in the pathogenesis of periodontal disease. It is associated with various body sites in humans, particularly in areas with high concentrations of anaerobic bacteria. Its presence in the oral microbiome highlights its significance in maintaining microbial balance and its potential contribution to oral health. The metabolic activities of Porphyromonas uenonis 60-3 contribute to the breakdown of collagen and other tissues, which can lead to gum inflammation and tooth loss if dysbiosis occurs. This microbe's ability to thrive in low-oxygen environments and its unique metabolic pathways enable it to outcompete certain pathogens, thereby influencing the overall composition of the oral microbiome. Porphyromonas uenonis 60-3 has been studied for its production of virulence factors and enzymes that facilitate tissue destruction during periodontal diseases. Understanding its genetics and biochemical pathways could provide insights into novel therapeutic approaches for managing periodontal infections and preserving oral health. Its role in interspecies interactions within biofilms also presents a fascinating area for further research in microbiology.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyPorphyromonadaceae
GenusPorphyromonas
SpeciesPorphyromonas uenonis
Strain60-3

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Porphyromonas uenonis 60-3
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatNot Available
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Porphyromonas uenonis 60-3 deg1118640599757, whole genome shotgun

Gene Summary

Adenine Count

536553 bp

Thymine Count

529805 bp

Guanine Count

587795 bp

Cytosine Count

588728 bp

Genome Length

2242885 bp

Protein-coding Genes

1977 genes

Non-Coding Genes

52 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ribosomal protein l29PORUE0001_1299Not AvailablePositive1379300 - 13794947601.92
30s ribosomal protein s17PORUE0001_1300Not AvailablePositive1379520 - 137977410148.3
ribosomal protein l14PORUE0001_1301Not AvailablePositive1379778 - 138014313297.4
ribosomal protein l24PORUE0001_1302Not AvailablePositive1380162 - 138048211611.4
ribosomal protein l5PORUE0001_1303Not AvailablePositive1380485 - 138103920848.8
ribosomal protein s14p/s29ePORUE0001_1304Not AvailablePositive1381055 - 138133310591.1
hypothetical proteinPORUE0001_1305Not AvailableNegative1381453 - 13816296394.63
ribosomal protein s8PORUE0001_1306Not AvailablePositive1381813 - 138220814740.3
ribosomal protein l6PORUE0001_1307Not AvailablePositive1382230 - 138278120689.2
ribosomal protein l18PORUE0001_1308Not AvailablePositive1382812 - 138315612585.3

Displaying genes 1291 – 1300 of 2029 in total

Metabolites

595 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000399(S)-allantoinC4H6N4O3Chemical structure of (S)-allantoin97-59-6
Average158.1154Da
Monoisotopic158.0439901Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000950L-xyluloseC5H10O5Chemical structure of L-xylulose527-50-4
Average150.1299Da
Monoisotopic150.05282343Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da

Displaying 1–10 of 595 metabolites

Health Effects

No health effects information available for this bacterium.