Staphylothermus hellenicus DSM 12710

CocciNon-motileAnaerobic

Kingdom

Thermoproteati

Phylum

Thermoproteota

Class

Thermoprotei

Order

Desulfurococcales

Family

Desulfurococcaceae

Genus

Staphylothermus

Description

Staphylothermus hellenicus is a hyperthermophilic heterotroph that requires sulfur for growth. It was isolated from a hydrothermal vent off Palaeochori Bay, Milos, Greece in 1996 at a depth of 9.4 m. It grows as non-flagellated regular cocci, 0.8 to 1.3 um in diameter, often forming large aggregates of up to 50 cells. Growth is optimal at 85 degrees C, pH 6 and prefers 4% NaCl. It is an obligate anaerobe. Staphylothermus hellenicus is closely related to Staphylothermus marinus, for which the genome sequence has been determined. There are several unique features in the S. marinus genome, including a sodium ion-translocating decarboxylase and three large membrane protein complexes related to the mbh and mbx genes of Pyrococcus furiosus. One or more of these membrane complexes is likely to be involved in sulfur reduction. It will be interesting to compare the two Staphylothermus genomes. As a hyperthermophile, S. hellenicus could serve as a source of heat-stable enzymes for biotechnology. (HAMAP: STAHD)

Taxonomy

KingdomThermoproteati
PhylumThermoproteota
ClassThermoprotei
OrderDesulfurococcales
FamilyDesulfurococcaceae
GenusStaphylothermus
SpeciesStaphylothermus hellenicus
StrainDSM 12710

Profile

Physiology
Gram staining propertiesNot Available
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature85
Temperature rangeHyperthermophilic
HabitatSpecialized
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementClusters
SporulationNonsporulating
Energy sourceHeterotroph
PathogenicityNo

Genome Summary

Staphylothermus hellenicus DSM 12710, complete sequence.

Gene Summary

Adenine Count

487633 bp

Thymine Count

510541 bp

Guanine Count

285234 bp

Cytosine Count

296939 bp

Genome Length

1580347 bp

Protein-coding Genes

1641 genes

Non-Coding Genes

43 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
adenosylmethionine decarboxylaseSHELL_RS04835Q4J8J9Positive957120 - 95750914582.5
nad(p)/fad-dependent oxidoreductaseSHELL_RS04840Not AvailablePositive957513 - 95863442734.3
asnc family transcriptional regulatorSHELL_RS04845Not AvailableNegative959058 - 95938112047.7
thiamine pyrophosphate-dependent enzymeSHELL_RS04850Q56317Negative959518 - 96057639210.3
transketolase c-terminal domain-containing proteinSHELL_RS04855O05651Negative960593 - 96185247003.9
4fe-4s binding proteinSHELL_RS04860Q56316Negative961867 - 96215710899.3
pyruvate ferredoxin oxidoreductase subunit gammaSHELL_RS04865O58411Negative962163 - 96272020241.9
transcriptional regulatorSHELL_RS04870Not AvailableNegative962932 - 96326712540.4
hypothetical proteinSHELL_RS04875Not AvailablePositive963601 - 96387310288.2
2-oxoacid:acceptor oxidoreductase subunit alphaSHELL_RS04880Q9YBX7Positive963897 - 96566365788.7

Displaying genes 991 – 1000 of 1684 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

69 records
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Result columns

Structure search compares stored SMILES, InChI, and InChIKey text. Exact mass must match the stored database value.

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Metabolite IDMetabolite nameStructureCAS number
Average massMonoisotopic mass
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000277keto-L-sorboseC6H12O6Chemical structure of keto-L-sorboseNot available
Average180.1559Da
Monoisotopic180.0633881Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm00006985-dehydro-2-deoxy-D-gluconateC6H9O6Chemical structure of 5-dehydro-2-deoxy-D-gluconateNot available
Average177.133Da
Monoisotopic177.04046159Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da
BASm0001279(6S)-5-methyl-5,6,7,8-tetrahydrofolateC20H23N7O6Chemical structure of (6S)-5-methyl-5,6,7,8-tetrahydrofolateNot available
Average457.4399Da
Monoisotopic457.1709815Da

Displaying 1–10 of 69 metabolites

Health Effects

No health effects information available for this bacterium.