Helicobacter pylori 35A

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori 35A is a Gram-negative bacterium characterized by its spiral shape and solitary cell arrangement. This microbe optimally thrives at a temperature of 37.0°C, which aligns with the typical human body temperature, indicating its adaptation to a host-associated habitat. As a microaerophilic organism, H. pylori 35A requires reduced levels of oxygen for growth, reflecting its specific ecological niche within the human gastric environment. The spiral morphology of H. pylori is thought to facilitate its motility, enabling the bacterium to navigate the viscous gastric mucus layer, thereby allowing it to colonize the stomach lining. The microaerophilic nature of this organism suggests that it has evolved mechanisms to survive and proliferate in the low-oxygen conditions prevalent in the gastric environment. This adaptation may also play a role in its interactions with the host's immune system and gastric microflora. Importantly, the ecological role of Helicobacter pylori 35A may extend beyond merely being a commensal organism. Its presence can influence gastric pH and local microbial communities, which can have implications for overall gastrointestinal health. Understanding the unique traits and ecological interactions of H. pylori 35A is crucial for elucidating its role in the human microbiome and potential impacts on host physiology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain35A

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori 35A
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori 35A, complete sequence.

Gene Summary

Adenine Count

477210 bp

Thymine Count

480532 bp

Guanine Count

302210 bp

Cytosine Count

306703 bp

Genome Length

1566655 bp

Protein-coding Genes

1474 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nicotinate (nicotinamide) nucleotide adenylyltransferaseHMPREF4655_RS07480Not AvailableNegative1526808 - 152732319662.2
nickel-responsive transcriptional regulator nikrHMPREF4655_RS07485Not AvailableNegative1527316 - 152776217046.2
tonb-system energizer exbbHMPREF4655_RS07490Not AvailablePositive1528080 - 152851715822.0
tonb system transport protein exbdHMPREF4655_RS07495Not AvailablePositive1528514 - 152890314361.3
energy transducer tonb family proteinHMPREF4655_RS07500Not AvailablePositive1528869 - 152972031327.5
site-specific dna-methyltransferaseHMPREF4655_RS08630Not AvailablePositive1530009 - 15301796394.86
agmatine deiminase family proteinHMPREF4655_RS07510Not AvailablePositive1530231 - 153122337558.2
carbamoyltransferase hypfHMPREF4655_RS07515Not AvailablePositive1531220 - 153347284671.5
hydrogenase expression/formation protein hypeHMPREF4655_RS07520Not AvailablePositive1533475 - 153447336294.5
gdp-l-fucose synthase family proteinHMPREF4655_RS07525Not AvailableNegative1534722 - 153565434815.5

Displaying genes 1481 – 1490 of 1519 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.