Helicobacter pylori 35A

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori 35A is a Gram-negative bacterium characterized by its spiral shape and solitary cell arrangement. This microbe optimally thrives at a temperature of 37.0°C, which aligns with the typical human body temperature, indicating its adaptation to a host-associated habitat. As a microaerophilic organism, H. pylori 35A requires reduced levels of oxygen for growth, reflecting its specific ecological niche within the human gastric environment. The spiral morphology of H. pylori is thought to facilitate its motility, enabling the bacterium to navigate the viscous gastric mucus layer, thereby allowing it to colonize the stomach lining. The microaerophilic nature of this organism suggests that it has evolved mechanisms to survive and proliferate in the low-oxygen conditions prevalent in the gastric environment. This adaptation may also play a role in its interactions with the host's immune system and gastric microflora. Importantly, the ecological role of Helicobacter pylori 35A may extend beyond merely being a commensal organism. Its presence can influence gastric pH and local microbial communities, which can have implications for overall gastrointestinal health. Understanding the unique traits and ecological interactions of H. pylori 35A is crucial for elucidating its role in the human microbiome and potential impacts on host physiology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain35A

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori 35A
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori 35A, complete sequence.

Gene Summary

Adenine Count

477210 bp

Thymine Count

480532 bp

Guanine Count

302210 bp

Cytosine Count

306703 bp

Genome Length

1566655 bp

Protein-coding Genes

1474 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uroporphyrinogen-iii synthaseHMPREF4655_RS06925Not AvailablePositive1433388 - 143406825784.4
fluoride efflux transporter crcbHMPREF4655_RS06930Not AvailablePositive1434115 - 143450714090.6
radical sam family heme chaperone hemwHMPREF4655_RS06935Not AvailableNegative1434550 - 143558739408.2
c-type cytochromeHMPREF4655_RS06940Not AvailablePositive1435683 - 143597310361.1
rna pyrophosphohydrolaseHMPREF4655_RS06945Not AvailablePositive1436133 - 143660618637.4
aspartate kinaseHMPREF4655_RS06950Not AvailablePositive1436600 - 143781744176.4
hoba family dna replication regulatorHMPREF4655_RS06955Not AvailablePositive1437814 - 143835621058.4
dna polymerase iii subunit delta'HMPREF4655_RS06960Not AvailablePositive1438353 - 143900925377.8
dihydropteroate synthaseHMPREF4655_RS06965Not AvailablePositive1439006 - 144014843055.9
hypothetical proteinHMPREF4655_RS06970Not AvailableNegative1440173 - 144063417361.3

Displaying genes 1371 – 1380 of 1519 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.