Helicobacter pylori 35A

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori 35A is a Gram-negative bacterium characterized by its spiral shape and solitary cell arrangement. This microbe optimally thrives at a temperature of 37.0°C, which aligns with the typical human body temperature, indicating its adaptation to a host-associated habitat. As a microaerophilic organism, H. pylori 35A requires reduced levels of oxygen for growth, reflecting its specific ecological niche within the human gastric environment. The spiral morphology of H. pylori is thought to facilitate its motility, enabling the bacterium to navigate the viscous gastric mucus layer, thereby allowing it to colonize the stomach lining. The microaerophilic nature of this organism suggests that it has evolved mechanisms to survive and proliferate in the low-oxygen conditions prevalent in the gastric environment. This adaptation may also play a role in its interactions with the host's immune system and gastric microflora. Importantly, the ecological role of Helicobacter pylori 35A may extend beyond merely being a commensal organism. Its presence can influence gastric pH and local microbial communities, which can have implications for overall gastrointestinal health. Understanding the unique traits and ecological interactions of H. pylori 35A is crucial for elucidating its role in the human microbiome and potential impacts on host physiology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain35A

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori 35A
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori 35A, complete sequence.

Gene Summary

Adenine Count

477210 bp

Thymine Count

480532 bp

Guanine Count

302210 bp

Cytosine Count

306703 bp

Genome Length

1566655 bp

Protein-coding Genes

1474 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
4fe-4s dicluster-binding proteinHMPREF4655_RS06320Not AvailablePositive1306876 - 130726815124.8
2-oxoacid:ferredoxin oxidoreductase subunit alphaHMPREF4655_RS06325Not AvailablePositive1307279 - 130850244784.3
thiamine pyrophosphate-dependent enzymeHMPREF4655_RS06330Not AvailablePositive1308515 - 130945934971.9
adenylosuccinate lyaseHMPREF4655_RS06335Not AvailablePositive1309569 - 131089149883.5
outer membrane proteinHMPREF4655_RS06340Not AvailablePositive1310953 - 131178631765.0
excinuclease abc subunit uvrbHMPREF4655_RS06345Not AvailableNegative1311797 - 131377375950.7
duf262 domain-containing proteinHMPREF4655_RS08455Not AvailableNegative1313901 - 131441618922.2
hp1117 family sel1-like repeat proteinHMPREF4655_RS06355Not AvailableNegative1314936 - 131570629208.8
gamma-glutamyltransferaseHMPREF4655_RS06360Not AvailableNegative1315970 - 131767361115.9
flagellar hook-associated protein flgkHMPREF4655_RS06365Not AvailableNegative1317878 - 131969868325.6

Displaying genes 1251 – 1260 of 1519 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.