Helicobacter pylori 35A

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori 35A is a Gram-negative bacterium characterized by its spiral shape and solitary cell arrangement. This microbe optimally thrives at a temperature of 37.0°C, which aligns with the typical human body temperature, indicating its adaptation to a host-associated habitat. As a microaerophilic organism, H. pylori 35A requires reduced levels of oxygen for growth, reflecting its specific ecological niche within the human gastric environment. The spiral morphology of H. pylori is thought to facilitate its motility, enabling the bacterium to navigate the viscous gastric mucus layer, thereby allowing it to colonize the stomach lining. The microaerophilic nature of this organism suggests that it has evolved mechanisms to survive and proliferate in the low-oxygen conditions prevalent in the gastric environment. This adaptation may also play a role in its interactions with the host's immune system and gastric microflora. Importantly, the ecological role of Helicobacter pylori 35A may extend beyond merely being a commensal organism. Its presence can influence gastric pH and local microbial communities, which can have implications for overall gastrointestinal health. Understanding the unique traits and ecological interactions of H. pylori 35A is crucial for elucidating its role in the human microbiome and potential impacts on host physiology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strain35A

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori 35A
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori 35A, complete sequence.

Gene Summary

Adenine Count

477210 bp

Thymine Count

480532 bp

Guanine Count

302210 bp

Cytosine Count

306703 bp

Genome Length

1566655 bp

Protein-coding Genes

1474 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolaseHMPREF4655_RS06270Not AvailableNegative1295972 - 129659822655.0
phosphogluconate dehydrataseHMPREF4655_RS06275Not AvailableNegative1296617 - 129844366645.9
glucose-6-phosphate dehydrogenaseHMPREF4655_RS06280Not AvailablePositive1298511 - 129978849390.5
6-phosphogluconolactonaseHMPREF4655_RS06285Not AvailablePositive1299799 - 130048225596.7
glucokinaseHMPREF4655_RS06290Not AvailablePositive1300469 - 130147936656.7
nad(p)-dependent alcohol dehydrogenaseHMPREF4655_RS06295Not AvailablePositive1301640 - 130268638599.7
glycosyltransferaseHMPREF4655_RS06300Not AvailableNegative1302698 - 130385845508.1
hypothetical proteinHMPREF4655_RS06305Not AvailablePositive1304046 - 130535350991.7
outer membrane proteinHMPREF4655_RS06310Not AvailableNegative1305360 - 130602224566.6
pyruvate flavodoxin oxidoreductase subunit gammaHMPREF4655_RS06315Not AvailablePositive1306300 - 130686020996.8

Displaying genes 1241 – 1250 of 1519 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.