Bifidobacterium longum subsp. infantis CCUG 52486

Bifidobacterium longum subsp. infantis CCUG 52486 is a Gram-positive, rod-shaped bacterium that thrives in a mesophilic temperature range, is classified as a heterotroph, and is an obligate anaerobe. This microbe is primarily found in the intestines of infants, where it plays a critical role in early gut colonization. It is prevalent in various body sites, including the gastrointestinal tract, oral cavity, and vaginal microbiota, highlighting its versatile presence in infants and young children. With its rod shape, Bifidobacterium longum subsp. infantis demonstrates a characteristic morphology that is particularly suited for its ecological niche in the gut. As a Gram-positive bacterium, it possesses a thick peptidoglycan layer, which contributes to its resistance against certain environmental stresses. The mesophilic temperature preference indicates that it thrives best at moderate temperatures, aligning with the warm environment of the human gastrointestinal tract. As a heterotroph, this microbe relies on organic compounds for growth and metabolism, consuming carbohydrates present in breast milk, especially human milk oligosaccharides (HMOs). This ability to utilize HMOs is crucial during infancy and aids in establishing a healthy gut microbiome. Being an obligate anaerobe means it cannot survive in the presence of oxygen, which is consistent with its habitat in the anaerobic conditions found within the intestines. Bifidobacterium longum subsp. infantis CCUG 52486 has gained significant attention for its potential health benefits, including immune system modulation, protection against gastrointestinal infections, and promotion of overall gut health. Its probiotic properties make it an essential component of many infant formulas and supplements, aiding in the development of a balanced and diverse gut microbiota during a critical period of growth and development.