Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
abc transporter atp-binding protein	HMPREF0837_RS04980	Not Available	Positive	951814 - 952578	28281.5
abc transporter atp-binding protein	HMPREF0837_RS04985	Not Available	Positive	952578 - 953288	25687.4
cbs domain-containing protein	HMPREF0837_RS04990	Not Available	Positive	953702 - 954358	24186.3
peptide chain release factor 2	HMPREF0837_RS04995	Not Available	Positive	954466 - 955561	41361.9
cell division atp-binding protein ftse	HMPREF0837_RS05000	Not Available	Positive	955579 - 956271	25798.4
permease-like cell division protein ftsx	HMPREF0837_RS05005	Not Available	Positive	956264 - 957190	34330.1
pts transporter subunit iibc	HMPREF0837_RS05010	Not Available	Positive	957476 - 959656	77893.5
endonuclease/exonuclease/phosphatase family protein	HMPREF0837_RS05015	Not Available	Positive	959708 - 960523	31158.6
dead/deah box helicase	HMPREF0837_RS05020	Not Available	Positive	960663 - 962006	50731.4
methionine adenosyltransferase	HMPREF0837_RS05025	Not Available	Positive	962383 - 963573	43175.9