Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
thiamine phosphate synthase	HMPREF0837_RS04825	Not Available	Positive	924844 - 925473	23273.2
ecf transporter s component	HMPREF0837_RS04830	Not Available	Positive	926032 - 926592	20310.4
atp-binding cassette domain-containing protein	HMPREF0837_RS04835	Not Available	Positive	926593 - 927978	52215.9
energy-coupling factor transporter transmembrane component t	HMPREF0837_RS04840	Not Available	Positive	927980 - 928630	24943.5
thiaminase ii	HMPREF0837_RS04845	Not Available	Positive	928641 - 929333	27389.5
energy coupling factor transporter s component thiw	HMPREF0837_RS04850	Not Available	Positive	929338 - 929862	19196.3
hydroxyethylthiazole kinase	HMPREF0837_RS04855	Not Available	Positive	929862 - 930665	29195.2
thiamine phosphate synthase	HMPREF0837_RS04860	Not Available	Positive	930658 - 931290	22759.6
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	HMPREF0837_RS04865	Not Available	Negative	931499 - 932290	28309.3
copy/tcry family copper transport repressor	HMPREF0837_RS04870	Not Available	Positive	932656 - 933051	15209.5