Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
hypothetical protein	HMPREF0837_RS04670	Not Available	Positive	896850 - 897077	8331.92
16s rrna pseudouridine(516) synthase	HMPREF0837_RS04675	Not Available	Negative	897117 - 897842	26990.0
translational gtpase typa	HMPREF0837_RS04680	Not Available	Positive	898004 - 899845	68187.5
duf3165 family protein	HMPREF0837_RS04685	Not Available	Positive	899865 - 900119	9454.56
lactococcin 972 family bacteriocin	HMPREF0837_RS04690	Not Available	Positive	900484 - 900783	11007.8
bacteriocin-associated integral membrane family protein	HMPREF0837_RS04695	Not Available	Positive	900854 - 902875	76187.0
abc transporter atp-binding protein	HMPREF0837_RS04700	Not Available	Positive	902877 - 903518	23973.3
udp-n-acetylmuramoyl-l-alanine--d-glutamate ligase	HMPREF0837_RS04705	Not Available	Positive	903622 - 904974	48462.3
udp-n-acetylglucosamine--n-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol n-acetylglucosamine transferase	HMPREF0837_RS04710	Not Available	Positive	904976 - 906034	39436.6
cell division protein divib	HMPREF0837_RS04715	Not Available	Positive	906044 - 907264	46659.7