Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
redoxin family protein	HMPREF0837_RS04570	Not Available	Positive	873811 - 874377	20776.8
peptide-methionine (r)-s-oxide reductase msrb	HMPREF0837_RS04575	Not Available	Positive	874388 - 875500	41964.1
response regulator transcription factor	HMPREF0837_RS04580	Not Available	Positive	875993 - 876730	28290.2
sensor histidine kinase	HMPREF0837_RS04585	Not Available	Positive	876727 - 878418	63611.3
tigr01440 family protein	HMPREF0837_RS04590	Not Available	Positive	878534 - 879097	20193.5
zmpa/zmpb/zmpc family metallo-endopeptidase	HMPREF0837_RS04595	Not Available	Positive	879119 - 884827	212173.0
aminodeoxychorismate synthase component i	HMPREF0837_RS04600	Not Available	Positive	884888 - 886609	65802.2
alpha/beta fold hydrolase	HMPREF0837_RS04605	Not Available	Positive	886610 - 887227	22890.1
n-acetylmuramoyl-l-alanine amidase family protein	HMPREF0837_RS04610	Not Available	Positive	887277 - 888275	37704.1
rok family glucokinase	HMPREF0837_RS04615	Not Available	Positive	888402 - 889361	33409.2