Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
hit family protein	HMPREF0837_RS03940	Not Available	Negative	750745 - 751155	15057.1
abc transporter atp-binding protein	HMPREF0837_RS03945	Not Available	Positive	751223 - 751954	27028.1
abc transporter permease	HMPREF0837_RS03950	Not Available	Positive	751951 - 753000	40655.3
hypothetical protein	HMPREF0837_RS03955	Not Available	Negative	753168 - 753497	12523.8
lyttr family dna-binding domain-containing protein	HMPREF0837_RS03960	Not Available	Positive	753773 - 754111	13465.3
response regulator transcription factor	HMPREF0837_RS03965	Not Available	Positive	754116 - 754853	28754.4
sensor histidine kinase	HMPREF0837_RS03970	Not Available	Positive	754866 - 756206	51998.8
is1380-like element isspn5 family transposase	HMPREF0837_RS03975	Not Available	Negative	756446 - 757792	51934.2
quorum-sensing system pheromone blpc	HMPREF0837_RS03980	Not Available	Negative	757959 - 758114	5848.0
bacteriocin secretion accessory protein	HMPREF0837_RS03985	Not Available	Negative	758171 - 759532	50647.1