Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
energy-coupling factor transporter transmembrane component t family protein	HMPREF0837_RS03785	Not Available	Positive	716089 - 716919	31630.6
trna (cytidine(34)-2'-o)-methyltransferase	HMPREF0837_RS03790	Not Available	Positive	717112 - 717615	19552.5
ecf transporter s component	HMPREF0837_RS03795	Not Available	Positive	718068 - 718631	20822.7
phosphatase pap2 family protein	HMPREF0837_RS03800	Not Available	Positive	718621 - 719271	24960.5
hypothetical protein	HMPREF0837_RS03805	Not Available	Positive	719298 - 719687	14815.5
gnat family n-acetyltransferase	HMPREF0837_RS03810	Not Available	Positive	719692 - 720141	17301.9
dna-directed rna polymerase subunit delta	HMPREF0837_RS03815	Not Available	Positive	720269 - 720856	22126.4
ctp synthase	HMPREF0837_RS03825	Not Available	Positive	721246 - 722853	59260.1
na/pi cotransporter family protein	HMPREF0837_RS03830	Not Available	Negative	723412 - 725043	59534.6
endo-beta-n-acetylglucosaminidase	HMPREF0837_RS03835	Not Available	Positive	725332 - 730272	182049.0