Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
duf4838 domain-containing protein	HMPREF0837_RS03735	Not Available	Positive	703971 - 705857	73988.7
pts lactose/cellobiose transporter subunit iia	HMPREF0837_RS03740	Not Available	Positive	706025 - 706369	13122.5
6-phospho-beta-galactosidase	HMPREF0837_RS03745	Not Available	Positive	706379 - 707791	54672.0
pts lactose transporter subunit iibc	HMPREF0837_RS03750	Not Available	Positive	707860 - 709539	61729.0
trkh family potassium uptake protein	HMPREF0837_RS03755	Not Available	Negative	709665 - 711104	52913.2
trk system potassium transporter trka	HMPREF0837_RS03760	Not Available	Negative	711108 - 712457	49777.1
s-adenosyl-l-methionine hydroxide adenosyltransferase family protein	HMPREF0837_RS03765	Not Available	Positive	712645 - 713493	31452.5
ecf-type riboflavin transporter substrate-binding protein	HMPREF0837_RS03770	Not Available	Positive	713508 - 714056	19344.4
hypothetical protein	HMPREF0837_RS12640	Not Available	Positive	714063 - 714320	9917.81
abc transporter atp-binding protein	HMPREF0837_RS03780	Not Available	Positive	714422 - 716104	62848.8