Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
beta-ketoacyl-acp synthase ii	HMPREF0837_RS03480	Not Available	Positive	650139 - 651374	43934.0
acetyl-coa carboxylase biotin carboxyl carrier protein	HMPREF0837_RS03485	Not Available	Positive	651377 - 651862	17034.4
3-hydroxyacyl-acp dehydratase fabz	HMPREF0837_RS03490	Not Available	Positive	651859 - 652281	15299.0
acetyl-coa carboxylase biotin carboxylase subunit	HMPREF0837_RS03495	Not Available	Positive	652293 - 653660	49542.4
acetyl-coa carboxylase, carboxyltransferase subunit beta	HMPREF0837_RS03500	Not Available	Positive	653697 - 654563	31787.8
acetyl-coa carboxylase carboxyl transferase subunit alpha	HMPREF0837_RS03505	Not Available	Positive	654560 - 655327	28235.2
biofilm-regulating peptide bric	HMPREF0837_RS03510	Not Available	Positive	655590 - 655775	7118.19
hypothetical protein	HMPREF0837_RS12925	Not Available	Positive	655793 - 656244	16741.4
cpbp family intramembrane glutamic endopeptidase	HMPREF0837_RS11470	Not Available	Positive	656299 - 656493	7933.73
transcription antitermination factor nusb	HMPREF0837_RS03515	Not Available	Negative	656543 - 656965	15965.1