Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
dtdp-4-dehydrorhamnose reductase	HMPREF0837_RS03225	Not Available	Positive	595643 - 596494	32335.8
hypothetical protein	HMPREF0837_RS12915	Not Available	Positive	596557 - 597653	39020.4
peptide abc transporter substrate-binding protein	HMPREF0837_RS03235	Not Available	Positive	597980 - 599962	73084.2
spgh101 family endo-alpha-n-acetylgalactosaminidase	HMPREF0837_RS03240	Not Available	Positive	600263 - 605566	196195.0
penicillin-binding protein pbp1a	HMPREF0837_RS03245	Not Available	Negative	605732 - 607891	79754.0
holliday junction resolvase recu	HMPREF0837_RS03250	Not Available	Negative	607888 - 608484	23099.8
duf1273 domain-containing protein	HMPREF0837_RS03255	Not Available	Positive	608551 - 609078	20721.4
cell division regulator gpsb	HMPREF0837_RS03260	Not Available	Positive	609148 - 609489	12870.2
Ncrna_class:rnase_p_rna	Not Available	Not Available	Positive	609510 - 609890	Not Available
class i sam-dependent rna methyltransferase	HMPREF0837_RS03270	Not Available	Positive	609975 - 611132	43250.4