Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
sugar transferase	HMPREF0837_RS03175	Not Available	Positive	585139 - 586500	51975.7
wecb/taga/cpsf family glycosyltransferase	HMPREF0837_RS03180	Not Available	Positive	586506 - 587249	28276.5
phosphorylcholine transferase licd	HMPREF0837_RS03185	Not Available	Positive	587246 - 588070	32144.8
glycosyltransferase	HMPREF0837_RS03190	Not Available	Positive	588072 - 588950	34511.2
o-antigen polymerase	HMPREF0837_RS03195	Not Available	Positive	588951 - 590285	51595.9
hypothetical protein	HMPREF0837_RS03200	Not Available	Positive	590313 - 591737	54656.1
non-hydrolyzing udp-n-acetylglucosamine 2-epimerase	HMPREF0837_RS03205	Not Available	Positive	591802 - 592890	40753.1
glucose-1-phosphate thymidylyltransferase rfba	HMPREF0837_RS03210	Not Available	Positive	593053 - 593922	32229.7
dtdp-4-dehydrorhamnose 3,5-epimerase family protein	HMPREF0837_RS03215	Not Available	Positive	593923 - 594516	22289.3
dtdp-glucose 4,6-dehydratase	HMPREF0837_RS03220	Not Available	Positive	594528 - 595577	39004.6