Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
competence type iv pilus minor pilin comgg	HMPREF0837_RS00230	Not Available	Negative	37212 - 37625	15893.1
competence type iv pilus minor pilin comgf	HMPREF0837_RS00235	Not Available	Negative	37603 - 38064	17856.3
competence type iv pilus minor pilin comge	HMPREF0837_RS00240	Not Available	Negative	38027 - 38329	11135.8
competence type iv pilus minor pilin comgd	HMPREF0837_RS00245	Not Available	Negative	38292 - 38696	14637.7
comg operon protein comgc	HMPREF0837_RS00250	Not Available	Negative	38689 - 39015	12190.0
competence type iv pilus assembly protein comgb	HMPREF0837_RS00255	Not Available	Negative	39017 - 40033	38527.0
competence type iv pilus atpase comga	HMPREF0837_RS00260	Not Available	Negative	39981 - 40922	35575.6
duf1033 family protein	HMPREF0837_RS00265	Not Available	Negative	40998 - 41363	15117.6
zinc-dependent alcohol dehydrogenase family protein	HMPREF0837_RS00270	Not Available	Negative	41514 - 42572	38093.9
n-acetylglucosamine-6-phosphate deacetylase	HMPREF0837_RS00275	Not Available	Negative	42735 - 43886	41699.5