Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
nramp family divalent metal transporter	HMPREF0837_RS02320	Not Available	Negative	426331 - 427593	45929.0
duf3021 domain-containing protein	HMPREF0837_RS02325	Not Available	Negative	427903 - 428361	17583.1
lyttr family dna-binding domain-containing protein	HMPREF0837_RS02330	Not Available	Negative	428358 - 428798	17170.8
hypothetical protein	HMPREF0837_RS13175	Not Available	Negative	428886 - 429011	4871.81
dna mismatch repair endonuclease mutl	HMPREF0837_RS02335	Not Available	Positive	429154 - 431103	73439.1
6,7-dimethyl-8-ribityllumazine synthase	HMPREF0837_RS02340	Not Available	Negative	431428 - 431895	16753.2
bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/gtp cyclohydrolase ii	HMPREF0837_RS02345	Not Available	Negative	431896 - 433101	45085.5
riboflavin synthase	HMPREF0837_RS02350	Not Available	Negative	433121 - 433756	23245.1
bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase ribd	HMPREF0837_RS02355	Not Available	Negative	433741 - 434841	40582.4
holliday junction branch migration protein ruva	HMPREF0837_RS02360	Not Available	Positive	435246 - 435839	21665.4