Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
metq/nlpa family abc transporter substrate-binding protein	HMPREF0837_RS02270	Not Available	Positive	416527 - 417381	31190.7
m20 family metallopeptidase	HMPREF0837_RS02275	Not Available	Positive	417481 - 418854	51475.0
methionine abc transporter atp-binding protein	HMPREF0837_RS02280	Not Available	Positive	418847 - 419908	38722.1
methionine abc transporter permease	HMPREF0837_RS02285	Not Available	Positive	419910 - 420602	24521.6
mptd family putative ecf transporter s component	HMPREF0837_RS02290	Not Available	Negative	420632 - 421201	20231.8
yesl family protein	HMPREF0837_RS02295	Not Available	Positive	421336 - 421950	22968.0
sensor histidine kinase	HMPREF0837_RS02300	Not Available	Positive	421928 - 423598	64421.8
response regulator transcription factor	HMPREF0837_RS02305	Not Available	Positive	423610 - 424896	49537.6
hypothetical protein	HMPREF0837_RS02310	Not Available	Positive	424957 - 425490	19836.6
class ib ribonucleoside-diphosphate reductase assembly flavoprotein nrdi	HMPREF0837_RS02315	Not Available	Positive	425568 - 426038	17569.9