Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
ribosomal protein s18-alanine n-acetyltransferase	HMPREF0837_RS02165	Not Available	Positive	399640 - 400077	16431.7
trna (adenosine(37)-n6)-threonylcarbamoyltransferase complex transferase subunit tsad	HMPREF0837_RS02170	Not Available	Positive	400067 - 401077	36231.3
hypothetical protein	HMPREF0837_RS02180	Not Available	Negative	401117 - 402423	50083.9
hypothetical protein	HMPREF0837_RS13260	Not Available	Negative	402759 - 403450	26794.2
glycosyltransferase family 4 protein	HMPREF0837_RS12895	Not Available	Positive	403693 - 404247	21365.4
glycosyltransferase family 4 protein	HMPREF0837_RS12900	Not Available	Positive	404375 - 404836	17356.0
glycosyltransferase family 2 protein	HMPREF0837_RS02205	Not Available	Positive	404860 - 405735	34052.3
atp-binding cassette domain-containing protein	HMPREF0837_RS02210	Not Available	Positive	405822 - 407438	61065.9
hypothetical protein	HMPREF0837_RS13405	Not Available	Positive	407458 - 407675	8536.52
hypothetical protein	HMPREF0837_RS02215	Not Available	Positive	407786 - 408214	16953.7