Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
hypothetical protein	HMPREF0837_RS12600	Not Available	Negative	367258 - 367662	15217.9
had family hydrolase	HMPREF0837_RS01975	Not Available	Negative	367712 - 368344	23575.1
l-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha	HMPREF0837_RS01980	Not Available	Negative	368366 - 369238	30380.4
l-serine ammonia-lyase, iron-sulfur-dependent subunit beta	HMPREF0837_RS01985	Not Available	Negative	369247 - 369918	24330.5
lysm peptidoglycan-binding domain-containing protein	HMPREF0837_RS01990	Not Available	Positive	370160 - 370747	20864.0
hypothetical protein	HMPREF0837_RS01995	Not Available	Negative	370799 - 371125	12935.9
lactococcin 972 family bacteriocin	HMPREF0837_RS02000	Not Available	Positive	371538 - 371819	10308.0
bacteriocin-associated integral membrane family protein	HMPREF0837_RS02005	Not Available	Positive	371874 - 373982	80823.1
abc transporter atp-binding protein	HMPREF0837_RS02010	Not Available	Positive	373979 - 374620	23627.8
abc transporter substrate-binding protein	HMPREF0837_RS02015	Not Available	Positive	374827 - 375633	29210.2