Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
atp-binding cassette domain-containing protein	HMPREF0837_RS01240	Not Available	Positive	234242 - 235864	60874.2
yfho family protein	HMPREF0837_RS01245	Not Available	Positive	235926 - 238478	97191.7
hypothetical protein	HMPREF0837_RS13250	Not Available	Negative	238509 - 239583	38536.7
tetr/acrr family transcriptional regulator	HMPREF0837_RS01260	Not Available	Positive	239763 - 240305	21275.7
Trna-asn	Not Available	Not Available	Positive	240346 - 240419	Not Available
Trna-glu	Not Available	Not Available	Positive	240425 - 240496	Not Available
competence system response regulator transcription factor come	HMPREF0837_RS01275	Not Available	Negative	240548 - 241300	29959.9
competence system sensor histidine kinase comd	HMPREF0837_RS01280	Not Available	Negative	241297 - 242622	51356.7
competence-stimulating peptide comc	HMPREF0837_RS01285	Not Available	Negative	242643 - 242768	4971.3
Trna-arg	Not Available	Not Available	Positive	242933 - 243006	Not Available