Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
energy-coupling factor transporter atpase	HMPREF0837_RS01190	Not Available	Negative	224106 - 224945	30527.1
energy-coupling factor abc transporter atp-binding protein	HMPREF0837_RS01195	Not Available	Negative	224930 - 225757	31104.1
cdp-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	HMPREF0837_RS01200	Not Available	Negative	225754 - 226299	20026.3
cytoskeleton protein rodz	HMPREF0837_RS01205	Not Available	Negative	226310 - 227131	30232.7
ef-p 5-aminopentanol modification-associated protein yfmh	HMPREF0837_RS01210	Not Available	Negative	227173 - 228456	48999.0
ef-p 5-aminopentanol modification-associated protein yfmf	HMPREF0837_RS01215	Not Available	Negative	228453 - 229703	48081.5
s4 domain-containing protein yaaa	HMPREF0837_RS01220	Not Available	Positive	229862 - 230230	13979.9
dna replication/repair protein recf	HMPREF0837_RS01225	Not Available	Positive	230233 - 231330	41918.5
imp dehydrogenase	HMPREF0837_RS01230	Not Available	Negative	231381 - 232859	52447.8
tryptophan--trna ligase	HMPREF0837_RS01235	Not Available	Negative	233011 - 234036	38420.0