Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
cysteine synthase a	HMPREF0837_RS01140	Not Available	Positive	216030 - 216950	31875.2
hypothetical protein	HMPREF0837_RS01145	Not Available	Negative	217025 - 217563	20886.3
hypothetical protein	HMPREF0837_RS01150	Not Available	Positive	217536 - 217844	12094.7
is66 family insertion sequence element accessory protein tnpb	HMPREF0837_RS01155	Not Available	Negative	217985 - 218308	12405.1
translation elongation factor ts	HMPREF0837_RS01160	Not Available	Negative	218554 - 219594	37363.6
30s ribosomal protein s2	HMPREF0837_RS01165	Not Available	Negative	219673 - 220452	28842.6
peptidoglycan hydrolase pcsb	HMPREF0837_RS01170	Not Available	Negative	220676 - 221854	41699.5
rod shape-determining protein mred	HMPREF0837_RS01175	Not Available	Negative	221948 - 222442	19325.7
rod shape-determining protein mrec	HMPREF0837_RS01180	Not Available	Negative	222442 - 223260	29740.5
energy-coupling factor transporter transmembrane component t family protein	HMPREF0837_RS01185	Not Available	Negative	223319 - 224113	29479.4