Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
ribulose-phosphate 3-epimerase	HMPREF0837_RS10890	Not Available	Negative	2060694 - 2061350	23944.8
ribosome small subunit-dependent gtpase a	HMPREF0837_RS10895	Not Available	Negative	2061361 - 2062239	33007.2
16s rrna (adenine(1518)-n(6)/adenine(1519)-n(6))- dimethyltransferase rsma	HMPREF0837_RS10900	Not Available	Negative	2062241 - 2063113	32239.1
hypothetical protein	HMPREF0837_RS13135	Not Available	Negative	2063364 - 2063657	11267.4
abc transporter atp-binding protein	HMPREF0837_RS10905	Not Available	Negative	2063650 - 2064291	23921.2
bacteriocin-associated integral membrane family protein	HMPREF0837_RS10910	Not Available	Negative	2064293 - 2066323	75413.1
helix-turn-helix transcriptional regulator	HMPREF0837_RS10915	Not Available	Negative	2066591 - 2067490	35422.1
ribonuclease m5	HMPREF0837_RS10920	Not Available	Negative	2067562 - 2068122	21506.7
tatd family hydrolase	HMPREF0837_RS10925	Not Available	Negative	2068122 - 2068895	28906.4
hypothetical protein	HMPREF0837_RS10930	Not Available	Negative	2069200 - 2070171	32987.5