Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
sigma-70 family rna polymerase sigma factor	HMPREF0837_RS10735	Not Available	Positive	2028602 - 2029024	16461.6
helix-turn-helix domain-containing protein	HMPREF0837_RS10740	Not Available	Positive	2029021 - 2029251	8944.09
hypothetical protein	HMPREF0837_RS13130	Not Available	Negative	2029477 - 2029728	9132.99
excisionase	HMPREF0837_RS10745	Not Available	Positive	2029712 - 2029915	8110.85
tyrosine-type recombinase/integrase	HMPREF0837_RS10750	Not Available	Positive	2029997 - 2031214	47024.5
duf1430 domain-containing protein	HMPREF0837_RS10755	Not Available	Positive	2032105 - 2034120	76244.9
abc transporter atp-binding protein	HMPREF0837_RS10760	Not Available	Positive	2034122 - 2034754	23698.6
nucleoside-diphosphate kinase	HMPREF0837_RS10770	Not Available	Negative	2035682 - 2036095	15440.5
dna-directed rna polymerase subunit beta'	HMPREF0837_RS10775	Not Available	Negative	2036206 - 2039883	136997.0
dna-directed rna polymerase subunit beta	HMPREF0837_RS10780	Not Available	Negative	2039916 - 2043527	134325.0