Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
hypothetical protein	HMPREF0837_RS13240	Not Available	Negative	195941 - 196897	36043.1
hypothetical protein	HMPREF0837_RS13245	Not Available	Negative	197108 - 197437	12345.9
isoprenylcysteine carboxyl methyltransferase family protein	HMPREF0837_RS01045	Not Available	Negative	197516 - 198043	20187.9
two-component system sensor histidine kinase hk06	HMPREF0837_RS01050	Not Available	Negative	198138 - 199469	50964.6
two-component system response regulator rr06	HMPREF0837_RS01055	Not Available	Negative	199466 - 200119	25205.9
atp-dependent clp protease atp-binding subunit	HMPREF0837_RS01065	Not Available	Negative	200761 - 203193	90175.1
ctsr family transcriptional regulator	HMPREF0837_RS01070	Not Available	Negative	203195 - 203653	17542.3
abc transporter atp-binding protein	HMPREF0837_RS01075	Not Available	Negative	203772 - 204500	27520.6
abc transporter substrate-binding protein	HMPREF0837_RS01080	Not Available	Negative	204500 - 205507	37778.6
abc transporter permease	HMPREF0837_RS01085	Not Available	Negative	205545 - 206303	28876.1