Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
tetracycline resistance ribosomal protection protein tet(m)	HMPREF0837_RS10680	Not Available	Positive	2019970 - 2021889	72560.5
hypothetical protein	HMPREF0837_RS10690	Not Available	Positive	2022253 - 2022498	8933.61
hypothetical protein	HMPREF0837_RS10695	Not Available	Positive	2022495 - 2022830	12675.3
hypothetical protein	HMPREF0837_RS10700	Not Available	Positive	2022843 - 2023211	14083.1
duf5960 family protein	HMPREF0837_RS10705	Not Available	Positive	2023198 - 2023497	12284.4
abc-f type ribosomal protection protein msr(d)	HMPREF0837_RS10710	Not Available	Negative	2023615 - 2025078	54877.4
macrolide efflux mfs transporter mef(a)	HMPREF0837_RS10715	Not Available	Negative	2025198 - 2026415	43927.6
hypothetical protein	HMPREF0837_RS10720	Not Available	Negative	2026801 - 2026971	6684.08
cysteine-rich ktr domain-containing protein	HMPREF0837_RS12150	Not Available	Positive	2027493 - 2027684	7259.93
helix-turn-helix transcriptional regulator	HMPREF0837_RS10730	Not Available	Negative	2027744 - 2028097	13545.3