Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
hypothetical protein	HMPREF0837_RS10590	Not Available	Negative	2002782 - 2003402	23542.1
helix-turn-helix domain-containing protein	HMPREF0837_RS10595	Not Available	Negative	2003708 - 2004571	34116.9
phra family quorum-sensing system peptide	HMPREF0837_RS13220	Not Available	Positive	2004762 - 2004932	6458.0
ydcp family protein	HMPREF0837_RS10605	Not Available	Positive	2005334 - 2005648	11921.3
ydcp family protein	HMPREF0837_RS10610	Not Available	Positive	2005664 - 2006050	14372.0
ftsk/spoiiie domain-containing protein	HMPREF0837_RS10615	Not Available	Positive	2006079 - 2007464	53372.4
hypothetical protein	HMPREF0837_RS12140	Not Available	Positive	2007467 - 2007619	5383.55
mobt family relaxase	HMPREF0837_RS10620	Not Available	Positive	2007642 - 2008904	49599.3
peptide-binding protein	HMPREF0837_RS10625	Not Available	Positive	2008849 - 2009061	8219.31
23s rrna methyltransferase attenuation leader peptide	HMPREF0837_RS10630	Not Available	Positive	2009110 - 2009193	3161.81