Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
imma/irre family metallo-endopeptidase	HMPREF0837_RS10540	Not Available	Negative	1994032 - 1994391	13689.3
hypothetical protein	HMPREF0837_RS10545	Not Available	Negative	1994437 - 1994643	7419.1
helix-turn-helix domain-containing protein	HMPREF0837_RS10550	Not Available	Negative	1994630 - 1994791	6092.49
n-acetylmuramoyl-l-alanine amidase lyta	HMPREF0837_RS10555	Not Available	Negative	1995150 - 1996106	36572.2
mate family efflux transporter	HMPREF0837_RS10560	Not Available	Negative	1996482 - 1997852	49787.3
recombinase reca	HMPREF0837_RS10565	Not Available	Negative	1998159 - 1999325	41952.2
competence/damage-inducible protein a	HMPREF0837_RS10570	Not Available	Negative	1999380 - 2000636	45092.1
biofilm formation/cell division transcriptional regulator brpa	HMPREF0837_RS10575	Not Available	Negative	2000721 - 2001737	37527.3
gnat family n-acetyltransferase	HMPREF0837_RS10580	Not Available	Negative	2001745 - 2002263	19398.4
trna (adenosine(37)-n6)-threonylcarbamoyltransferase complex atpase subunit type 1 tsae	HMPREF0837_RS10585	Not Available	Negative	2002253 - 2002696	16414.8