Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
yebc/pmpr family dna-binding transcriptional regulator	HMPREF0837_RS10445	Not Available	Negative	1976355 - 1977071	25831.1
cholesterol-dependent cytolysin pneumolysin	HMPREF0837_RS10450	Not Available	Negative	1977952 - 1979367	52901.2
hypothetical protein	HMPREF0837_RS10455	Not Available	Negative	1979378 - 1979788	15905.5
hypothetical protein	HMPREF0837_RS10460	Not Available	Negative	1979781 - 1980389	23320.2
duf4231 domain-containing protein	HMPREF0837_RS10465	Not Available	Negative	1980402 - 1980860	17412.3
hypothetical protein	HMPREF0837_RS13450	Not Available	Positive	1980985 - 1981116	5056.07
hypothetical protein	HMPREF0837_RS12125	Not Available	Positive	1981094 - 1981384	11055.6
glycerophosphodiester phosphodiesterase family protein	HMPREF0837_RS10475	Not Available	Positive	1981861 - 1982694	31797.4
extracellular solute-binding protein	HMPREF0837_RS10480	Not Available	Positive	1982745 - 1983806	39608.5
abc transporter atp-binding protein	HMPREF0837_RS10485	Not Available	Positive	1983823 - 1984827	37882.8