Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
duf4651 domain-containing protein	HMPREF0837_RS10390	Not Available	Negative	1970728 - 1971027	11134.4
hypothetical protein	HMPREF0837_RS13215	Not Available	Positive	1971121 - 1971252	4854.75
hypothetical protein	HMPREF0837_RS12105	Not Available	Negative	1971277 - 1971474	7149.2
liaf transmembrane domain-containing protein	HMPREF0837_RS10410	Not Available	Negative	1971717 - 1972391	24642.1
lyttr family dna-binding domain-containing protein	HMPREF0837_RS10415	Not Available	Negative	1972396 - 1972842	17433.8
phosphatase pap2 family protein	HMPREF0837_RS10420	Not Available	Negative	1972956 - 1973459	18828.7
duf2200 domain-containing protein	HMPREF0837_RS10425	Not Available	Negative	1973456 - 1973818	13782.7
hypothetical protein	HMPREF0837_RS13110	Not Available	Negative	1973884 - 1974729	30989.9
abc transporter permease	HMPREF0837_RS13115	Not Available	Negative	1974922 - 1975743	30654.2
hypothetical protein	HMPREF0837_RS10440	Not Available	Negative	1975760 - 1976231	18205.3