Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
hypothetical protein	HMPREF0837_RS12780	Not Available	Negative	1963445 - 1963876	17403.0
helix-turn-helix domain-containing protein	HMPREF0837_RS10345	Not Available	Negative	1963968 - 1964300	12890.1
class i sam-dependent methyltransferase	HMPREF0837_RS10350	Not Available	Negative	1964313 - 1965086	29762.6
hypothetical protein	HMPREF0837_RS10355	Not Available	Negative	1965534 - 1966289	29027.6
chaperonin groel	HMPREF0837_RS10360	Not Available	Negative	1966427 - 1968049	57098.8
co-chaperone groes	HMPREF0837_RS10365	Not Available	Negative	1968065 - 1968349	9898.95
single-stranded dna-binding protein	HMPREF0837_RS10370	Not Available	Negative	1968505 - 1968900	14908.7
sdr family nad(p)-dependent oxidoreductase	HMPREF0837_RS10375	Not Available	Negative	1968978 - 1969739	27611.4
ytpr family trna-binding protein	HMPREF0837_RS10380	Not Available	Negative	1969772 - 1970398	22926.7
thioredoxin family protein	HMPREF0837_RS10385	Not Available	Negative	1970414 - 1970731	12220.8