Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
hypothetical protein	HMPREF0837_RS10140	Not Available	Positive	1935698 - 1935883	7236.98
atp-binding cassette domain-containing protein	HMPREF0837_RS10145	Not Available	Negative	1935958 - 1936884	34798.9
abc transporter atp-binding protein	HMPREF0837_RS10150	Not Available	Negative	1936895 - 1937962	39439.2
oligopeptide abc transporter permease oppc	HMPREF0837_RS10155	Not Available	Negative	1937971 - 1938897	34622.7
abc transporter permease	HMPREF0837_RS10160	Not Available	Negative	1938897 - 1940393	55684.4
peptide abc transporter substrate-binding protein	HMPREF0837_RS10165	Not Available	Negative	1940460 - 1942439	72494.8
o-antigen ligase family protein	HMPREF0837_RS10170	Not Available	Negative	1943125 - 1944318	45210.6
sucrose phosphorylase	HMPREF0837_RS10175	Not Available	Negative	1944456 - 1945898	55842.6
hypothetical protein	HMPREF0837_RS13105	Not Available	Negative	1946082 - 1946249	6542.71
carbohydrate abc transporter permease	HMPREF0837_RS10185	Not Available	Negative	1946256 - 1947089	31576.5