Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
hypothetical protein	HMPREF0837_RS10030	Not Available	Positive	1917170 - 1917364	7389.94
abc transporter permease	HMPREF0837_RS10035	Not Available	Positive	1917661 - 1918620	35393.4
iron chelate uptake abc transporter family permease subunit	HMPREF0837_RS10040	Not Available	Positive	1918610 - 1919566	36251.0
abc transporter atp-binding protein	HMPREF0837_RS10045	Not Available	Positive	1919563 - 1920315	28501.7
siderophore abc transporter substrate-binding protein	HMPREF0837_RS10050	Not Available	Positive	1920411 - 1921376	34762.7
membrane protein insertion efficiency factor yidd	HMPREF0837_RS10055	Not Available	Negative	1921601 - 1921843	9336.59
pseudouridine synthase	HMPREF0837_RS10060	Not Available	Negative	1921843 - 1922565	27129.0
smc-scp complex subunit scpb	HMPREF0837_RS10065	Not Available	Negative	1922552 - 1923121	21039.2
segregation/condensation protein a	HMPREF0837_RS10070	Not Available	Negative	1923140 - 1923868	28287.3
site-specific tyrosine recombinase xerd	HMPREF0837_RS10075	Not Available	Negative	1923868 - 1924602	28490.6