Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
cation diffusion facilitator family transporter czcd	HMPREF0837_RS09980	Not Available	Negative	1907645 - 1908535	33128.6
tetr/acrr family transcriptional regulator scza	HMPREF0837_RS09985	Not Available	Positive	1908668 - 1909204	21234.3
nicotinamide riboside transporter pnuc	HMPREF0837_RS09990	Not Available	Negative	1909371 - 1910177	31032.0
abc transporter permease/substrate-binding protein	HMPREF0837_RS09995	Not Available	Negative	1910522 - 1912042	55520.4
abc transporter atp-binding protein	HMPREF0837_RS10000	Not Available	Negative	1912035 - 1912763	27090.9
nuclear transport factor 2 family protein	HMPREF0837_RS10005	Not Available	Negative	1912778 - 1913542	29398.0
marr family winged helix-turn-helix transcriptional regulator	HMPREF0837_RS10010	Not Available	Negative	1913546 - 1913989	16709.1
bacteriocin immunity protein	HMPREF0837_RS10015	Not Available	Negative	1914671 - 1914967	11228.7
glutamyl aminopeptidase	HMPREF0837_RS10020	Not Available	Negative	1914989 - 1916053	38021.4
udp-glucose 4-epimerase gale	HMPREF0837_RS10025	Not Available	Positive	1916454 - 1917173	26677.8