Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
xanthine phosphoribosyltransferase	HMPREF0837_RS09930	Not Available	Positive	1898343 - 1898924	20942.6
nucleobase:cation symporter-2 family protein	HMPREF0837_RS09935	Not Available	Positive	1898924 - 1900186	44166.6
dpnd/pcfm family protein	HMPREF0837_RS09940	Not Available	Negative	1900237 - 1900698	18058.3
type-2 restriction enzyme dpni	HMPREF0837_RS09945	Not Available	Negative	1900695 - 1901459	29786.7
paai family thioesterase	HMPREF0837_RS09950	Not Available	Negative	1901640 - 1902044	14876.8
udp-glucose--hexose-1-phosphate uridylyltransferase	HMPREF0837_RS09955	Not Available	Negative	1902114 - 1903595	56320.0
galactokinase	HMPREF0837_RS09960	Not Available	Negative	1903614 - 1904792	43556.5
dna-binding transcriptional regulator galr	HMPREF0837_RS09965	Not Available	Positive	1904957 - 1905964	37881.2
zinc-binding dehydrogenase	HMPREF0837_RS09970	Not Available	Negative	1906010 - 1907047	36784.0
stress response transcriptional regulator nmlr	HMPREF0837_RS09975	Not Available	Negative	1907048 - 1907401	13464.2