Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
glycosyl hydrolase family 28-related protein	HMPREF0837_RS09875	Not Available	Negative	1886375 - 1888453	75855.2
degt/dnrj/eryc1/strs family aminotransferase	HMPREF0837_RS09880	Not Available	Negative	1889374 - 1890600	45485.2
sugar transferase	HMPREF0837_RS09885	Not Available	Negative	1890643 - 1891335	26774.9
abc transporter atp-binding protein	HMPREF0837_RS09890	Not Available	Negative	1891519 - 1893261	65190.2
abc transporter atp-binding protein	HMPREF0837_RS09895	Not Available	Negative	1893251 - 1894996	65181.3
duf421 domain-containing protein	HMPREF0837_RS09905	Not Available	Negative	1895202 - 1895498	10895.0
hypothetical protein	HMPREF0837_RS12770	Not Available	Negative	1895651 - 1896106	17201.7
exodeoxyribonuclease iii	HMPREF0837_RS09915	Not Available	Positive	1896240 - 1897067	31093.5
voc family protein	HMPREF0837_RS09920	Not Available	Positive	1897079 - 1897330	9621.53
hypothetical protein	HMPREF0837_RS09925	Not Available	Positive	1897337 - 1897465	5140.25