Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
hypothetical protein	HMPREF0837_RS09820	Not Available	Negative	1876525 - 1876892	14549.2
mgtc/sapb family protein	HMPREF0837_RS09825	Not Available	Negative	1876988 - 1877698	25552.5
abc transporter permease	HMPREF0837_RS09830	Not Available	Negative	1877701 - 1879392	62668.6
abc transporter atp-binding protein	HMPREF0837_RS09835	Not Available	Negative	1879404 - 1880414	37473.0
extracellular solute-binding protein	HMPREF0837_RS09840	Not Available	Negative	1880517 - 1881584	39212.8
duf1868 domain-containing protein	HMPREF0837_RS09845	Not Available	Negative	1881609 - 1882268	26098.2
udp-glucose 4-epimerase gale	HMPREF0837_RS09850	Not Available	Negative	1882435 - 1883445	37140.4
udp-glucose--hexose-1-phosphate uridylyltransferase	HMPREF0837_RS09855	Not Available	Negative	1883458 - 1884933	56276.2
phosphate signaling complex phou family protein	HMPREF0837_RS09860	Not Available	Negative	1884946 - 1885587	25151.7
protein phosphatase 2c domain-containing protein	HMPREF0837_RS12070	Not Available	Negative	1885645 - 1886391	28427.8