Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
hypothetical protein	HMPREF0837_RS12065	Not Available	Positive	1867754 - 1867864	4142.57
tryptophan synthase subunit alpha	HMPREF0837_RS09770	Not Available	Negative	1867836 - 1868612	27698.4
tryptophan synthase subunit beta	HMPREF0837_RS09775	Not Available	Negative	1868605 - 1869828	44252.7
phosphoribosylanthranilate isomerase	HMPREF0837_RS09780	Not Available	Negative	1869806 - 1870405	21309.3
indole-3-glycerol phosphate synthase trpc	HMPREF0837_RS09785	Not Available	Negative	1870392 - 1871159	28888.6
anthranilate phosphoribosyltransferase	HMPREF0837_RS09790	Not Available	Negative	1871156 - 1872160	35964.9
aminodeoxychorismate/anthranilate synthase component ii	HMPREF0837_RS09795	Not Available	Negative	1872171 - 1872737	20874.9
anthranilate synthase component i	HMPREF0837_RS09800	Not Available	Negative	1872734 - 1874095	51251.3
hypothetical protein	HMPREF0837_RS13100	Not Available	Negative	1874467 - 1874808	13154.2
laci family dna-binding transcriptional regulator	HMPREF0837_RS09815	Not Available	Negative	1875416 - 1876417	37661.5