Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
glsb/yeaq/ymge family stress response membrane protein	HMPREF0837_RS09720	Not Available	Positive	1862006 - 1862170	5351.74
alkaline shock response membrane anchor protein amap	HMPREF0837_RS09725	Not Available	Positive	1862254 - 1862820	21816.2
duf2273 domain-containing protein	HMPREF0837_RS09730	Not Available	Positive	1862832 - 1863002	6302.04
asp23/gls24 family envelope stress response protein	HMPREF0837_RS09735	Not Available	Positive	1863041 - 1863649	21817.5
csbd family protein	HMPREF0837_RS09740	Not Available	Positive	1863680 - 1863883	7020.31
transposase	HMPREF0837_RS09745	Not Available	Negative	1863993 - 1864286	11526.3
gnat family n-acetyltransferase	HMPREF0837_RS09750	Not Available	Negative	1864410 - 1864856	17257.7
prepilin peptidase	HMPREF0837_RS09755	Not Available	Positive	1864926 - 1865585	24881.4
helix-turn-helix domain-containing protein	HMPREF0837_RS09760	Not Available	Negative	1865637 - 1866788	44815.9
hypothetical protein	HMPREF0837_RS09765	Not Available	Negative	1866803 - 1867534	28392.3